The increasing need for sustainable solutions to global challenges in health, agriculture, environmental management, and resource utilization has highlighted the importance of translational research and biotechnology-driven innovations. Translational research serves as a bridge between fundamental scientific discoveries and their practical applications, enabling the development of technologies and strategies that generate tangible societal benefits. This Special Issue aims to showcase recent advances in translational research, biotechnology, and sustainable bio-innovations that contribute to environmental sustainability, biodiversity conservation, agricultural productivity, public health, and bio-based economic development.

This Special Issue is inspired by the research contributions presented at the International Conference on Translational Research, Innovation and Bio-Entrepreneurship (TRIBE-2026). The collection brings together interdisciplinary studies that demonstrate innovative applications of biological sciences and biotechnology to address contemporary challenges. The published works encompass diverse areas, including molecular and computational biology, biodiversity assessment, phytochemical and antioxidant studies, environmental biotechnology, wastewater treatment, bioremediation, antimicrobial resistance, sustainable agriculture, dairy science, climate-resilient farming practices, bioresource utilization, and circular bioeconomy approaches.

The primary objective of this Special Issue is to provide a platform for researchers, academicians, industry experts, and policymakers to disseminate novel findings and foster collaboration across disciplines. By highlighting translational approaches and sustainable innovations, the issue seeks to encourage the development of science-based solutions with practical applications and societal impact.

The Special Issue welcomes original research articles, review papers, short communications, and case studies that advance knowledge in translational biology, biotechnology, environmental sustainability, bioresource management, agricultural innovations, and bio-entrepreneurship. Through this collection, we aim to promote scientific excellence, innovation, and sustainable development while strengthening the link between research outcomes and real-world applications.