Volume 5, Issue 1, March 2020, Page: 21-25
Analytical and Spectral Study of Furan Ring Containing Organic Ligands
Harshadkumar P. Patel, Faculty of Chemistry, S. S. Polytechnic College, Visnagar, India
Received: Dec. 12, 2019;       Accepted: Dec. 26, 2019;       Published: Jan. 30, 2020
DOI: 10.11648/j.cbe.20200501.14      View  230      Downloads  50
Abstract
The reaction of Ethyl 5-(piperidin-1-yl-methyl)furan-2-carboxylate with 4-amino salicylic acid afford a 4-(5-((diphenylamino)methyl)furan-2-carboxamido)-2-hydroxybenzoic acid (PFSA). The transition metal complexes of Cu2+, Co2+, Ni2+, Mn2+ and Zn2+ of PFSA have been prepared. The objective of the research work is synthesis, characterization and chelating properties of furan ring containing organic ligands. To monitor its antimicrobial activity. PFSA and all the metal complexes were characterized by elemental analyses, spectral studies, magnetic moment determination, molar conductivity measurement. The free ligand and it’s complexes have been tested for their antibacterial activities against two types of human pathogenic bacteria the first group is gram positive while the second group is gram negative (by using agar well diffusion method). Finally, it was found that compounds show different activity of inhibition on growth of the bacteria. The conclusion is Ni (II) Cu (II), Co (II) and Mn (II) complexes possess octahedral geometry around the central metal ion.
Keywords
Ethyl 5-(Piperidin-1-yl-methyl) Furan-2-Carboxylate, 4-Amino Salicylic Acid, Metal Chelates, Complexes, Spectral Studies, Magnetic Moment, Antibacterial and Antifungal Activity
To cite this article
Harshadkumar P. Patel, Analytical and Spectral Study of Furan Ring Containing Organic Ligands, Chemical and Biomolecular Engineering. Vol. 5, No. 1, 2020, pp. 21-25. doi: 10.11648/j.cbe.20200501.14
Copyright
Copyright © 2020 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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